London: A new study revealed that a rogue gene is responsible for depression. According to the researchers from ‘Kings College London’ a section of DNA is responsible for depression.

It is reported that this particular region, known as chromosome 3p25-26 -- contains up to 40 genes and one or more probably causes the condition which is notoriously difficult to manage.

Over the next year the team hopes to carry out more work to try and pinpoint exactly which gene is responsible.

Though depression is often triggered by traumatic events -- such as grief, redundancy or divorce -- scientists have long known that certain people are more susceptible.

In the study, the researchers examined the DNA of more than 800 British families with two or more siblings with depression.

At the same time, another team of scientists from the Washington University Medical School in St Louis, the US, looked at 91 families in Australia and 25 families in Finland.

The finding showed that the depressed siblings had the same genetic variations in the same section of their DNA.

This would suggest that depression runs in families, with people inheriting the genes from their parents, the researchers said.

Lead author Gerome Breen, from the Institute of Psychiatry in Kings College London, said, "In a large number of families where two or more members have depression we found robust evidence that a region called chromosome 3p25-26 is strongly linked to the disorder.”

Breen said, “Though these findings will not result in a test for depression they will help us track down specific genes that are altered in people with this disease.”

Marjorie Wallace, Chief Executive of the mental health charity Sane, said, "It is very exciting that there seems to be progress finding the gene involved in some people developing depression. However, we are still some distance from identifying the culprit' gene."

(Agencies)