UNICEF said in a statement that 200,000 youngsters more than a third need psycho-social support.

Ukraine remains locked in conflict with Moscow, which annexed the Crimean Peninsula and has supported a pro-Russian insurgency in the east. Fighting there has killed more than 9,000 people since April 2014 and devastated the nation's industrial heartland.

"Two years of violence, shelling and fear have left an indelible mark on thousands of children in eastern Ukraine," said Giovanna Barberis, UNICEF's representative in Ukraine.

Earlier this year, UNICEF called for an additional USD 54.3 million to address the humanitarian needs of the most vulnerable children in conflict-affected areas.

The agency warned that plummeting temperatures, fuel shortages and high prices for coal are leaving children at risk of respiratory infections. And it said the lack of access to health services and a shortage of medicines are threatening more disease outbreaks.

UNICEF said it has been working with partners to provide children with basic services.

The agency said it reached 1.6 million people with safe water, over 164,000 children and adults with essential hygiene items, and over 200,000 children with education kits and school supplies.

Read more: One in nine children globally live in conflict zones: UNICEF

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