According to the team from University of Birmingham, the findings present the possibility of new therapies for patients with non-alcoholic fatty liver disease, for which there is no current licensed treatment.

Non-alcoholic fatty liver disease (NAFLD) describes a wide range of conditions caused by a build-up of fat within the liver cells, usually seen in people who are overweight or obese.

Non-alcoholic steatohepatitis (NASH) is the more serious form of NAFLD and can ultimately increase the risk of total liver failure which means a transplant is required.

The trial demonstrated that 48 weeks of treatment with the drug named liraglutide resulted in four out of 10 patients clearing evidence of NASH from their livers. Because there are no licensed treatments available for non-alcoholic fatty liver disease, there is a large unmet clinical need.

It is administered in the form of an injection which the patient self-injects, which means the treatment could be administered at home.

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