Trump, 69, was also leading in Michigan where Ohio Governor John Kasich initially gave him a tough fight.

"Thank you Mississippi!", Trump, the billionaire real estate mogul, tweeted as results came in from the southern state of Mississippi which held Republican primary yesterday.

Clinton, 68, won the Democratic primary contest in Mississippi where she beat her party rival Bernie Sanders, 74.

With Mississippi win, Clinton has grabbed 21 delegates at stake taking her total count to 1134. To win the party's Presidential nomination, she needs 2384 delegates of the total 4765.

Before yesterday's primaries, Trump was leading with 384 delegates. He needs to win at least 1237 votes out of a total of 2472 available delegates.

Texas Senator Ted Cruz, 45, follows Trump with 300 delegates and Florida Senator Marco Rubio, 44, with 151 delegates.

In addition to Michigan and Mississippi, Presidential primaries are also being held in Hawaii and Idaho.

In Michigan, Sanders had earned the support of over half of the Democratic voters as against 47 percent for Clinton.

In Michigan, Trump was leading by 37.8 percent of the votes, followed by 26.9 percent of the Republican votes gained by Kasich.

On the other hand, Trump had support of 50.7 percent of the votes last counted, followed by 37.3 percent for Cruz.

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