Hales appears set to become captain Alastair Cook's new opening partner after being named in the Royal London Series squad to face India. (Agencies)
The 25-year-old, uncapped as yet in one-day internationals has played 32 T20 Internationals for England, joins a squad which will be missing frontline seamer Stuart Broad -- due to see a specialist this week to assess what to do about his long-term knee injury.
Back-in-favour Steven Finn has also been named in the squad.
Fast bowler James Anderson is included, despite suggestions that he might benefit from a rest after England concluded their sequence of five back-to-back Test matches with a 3-1 Investec Series victory over India on Sunday.
All-rounder Ben Stokes, who was dropped after the second Test against India, is also in the team.
There is no place for all-rounder and limited-overs regular Ravi Bopara in the squad.
The five-match ODI series begins at Bristol on August 25. It will be followed by a T20 international at Edgbaston on September 7.
England completed a 3-1 Test series win over India with an innings-and-244-run win at The Oval on Sunday.
England one-day squad: Alastair Cook (capt), Moeen Ali, James Anderson, Gary Ballance, Ian Bell, Jos Buttler (wk), Steven Finn, Harry Gurney, Alex Hales, Chris Jordan, EoinMorgan, Joe Root, Ben Stokes, James Tredwell, Chris Woakes.
Hales appears set to become captain Alastair Cook's new opening partner after being named in the Royal London Series squad to face India.