PSG, without injured spearhead Zlatan Ibrahimovic, do not actually need to score any goals at Stamford Bridge to knock Chelsea out following their 3-1 first leg win in Paris.
It probably will not be as simple as that though, as Chelsea know a 2-0 win will see them through on the away goals rule.
Even if his strikers again fail to impress Mourinho, Chelsea have an array of midfielders capable of swinging the tie in favour of the London club.
PSG do, though, start the match with a healthy advantage after Javier Pastore's goal with the last kick of the game at the Parc des Princes last week gave them a buffer.
However, Chelsea at Stamford Bridge are a different proposition to the team that have lost their last three away matches in all competitions.
On Saturday they brushed Stoke City aside 3-0 in the Premier League, with all three goals coming from midfielders: Mohamed Salah, Willian and Frank Lampard, who has now scored 250 club goals for West Ham United, Swansea City and Chelsea. He also has another 29 for England.
Saturday's match was also their eighth successive home game with conceding a goal, and kept them two points behind Liverpool in the Premier League title race.
It was their 77th unbeaten home league match in Mourinho's two spells at the club, and they have also proved in the past in Europe, most recently against Napoli two seasons ago, that no task is to large for them to overcome at Stamford Bridge.
Mourinho was not in charge of Chelsea when they overturned a 3-1 first leg defeat by Napoli in the round of 16 in 2012, winning 4-1 at home in the return match before going on to win the trophy in Munich.
While he has never lost a quarter-final tie with Porto, Chelsea, Inter Milan or Real Madrid, he has also never overturned a two-goal first leg deficit in European competition.


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