Scientists found that mice who spent time on a running wheel were able to shrink tumours to 50 percent of the size, compared to their less active counterparts.
Researchers next used mice depleted of NK cells to show that the increase in number of NK cells at the site of the tumour was directly contributing to the reduction in size.
Even with exercise and a full suite of other immune cells, without the NK cells these mice experienced the normal rate of cancer growth.
Blocking the function of adrenaline also blunted the cancer-killing benefits of the running wheel.
While the research is hopeful for patients looking for inexpensive ways to manage their cancer, more needs to be learned about the effects of exercise on metastasis and longevity, as well as if the observations hold true in humans.

The study was published in the journal Cell Metabolism.


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