In excerpts from a speech he will deliver in Miami to announce his candidacy, Republican Bush said, "I will take nothing and no one for granted. I will run with heart. I will run to win."
Son of one president and brother of another, Bush is searching for momentum to break out of a crowded field for the Republican presidential nomination to run in the November 2016 election.
Bush, 62, presented himself as an anti-Washington figure with a can-do spirit, ready to apply conservative principles that he says he used in Florida. Bush is only the latest candidate to paint himself as a Washington outsider and blame government for America's problems.
"We will take Washington - the static capital of this dynamic country - out of the business of causing problems," according to one excerpt of his speech.

"We will get back on the side of free enterprise and free people. I know we can fix this. Because I've done it," he said.

Bush will make his announcement at 3 p.m. EDT (1900 GMT) at Miami-Dade College, a school whose multicultural student population was chosen to emphasize Bush's commitment to trying to expand the appeal of the white-dominated Republican Party.

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