The temporal-parietal junction, or TP, which is found under the temporal bones near the ears, integrates the processing of social information as expressed in others' faces and voices, a function that is impaired in those with autism spectrum disorders.

Sex differences in this area of the brain may be a clue as to why males are at higher risk for certain forms of autism spectrum disorders, researchers said. Many early-onset neurodevelopmental disorders, including autism spectrum disorders, are more common in males than females.

Rebecca Knickmeyer and colleagues at the University of North Carolina-Chapel Hill have been characterizing sex differences in brain development in a group of over 800 normal newborns, who are assessed until they are two years old.

Another main finding in Knickmeyer's work is that by the age of two, myelination of long fibre tracks in the brain is more developed in males than in females.

This suggests that inferior parietal lobe volume can be influenced, at least in females, by sex chromosomes. The findings were presented recently at the annual meeting of the American College of Neuropsychopharmacology.



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