John Mathers, Professor of Human Nutrition from the Institute of Cellular Medicine at Newcastle University in the UK has found a link between excess body weight and risk of bowel cancer, also known as colorectal cancer (CRC).
Mathers found an overall increase of 18 percent in relative risk of CRC per 5 unit increase in body mass index (BMI).
"In addition, in men, there is now evidence that increasing waist circumference in middle age is associated with increased bowel cancer risk," said Mathers.
CRC risk was increased by nearly 60 per cent in men who gained at least 10 cm in waist circumference over 10 years. "This increased cancer risk may be due to persistent inflammation in people with obesity," Mathers said.
In his studies with Lynch Syndrome patients, Mathers  observed that aspirin lowered the excess CRC risk seen in patients with obesity, perhaps through its anti-inflammatory effects.
The research was presented at the 23rd United European Gastroenterology Week in Barcelona, Spain.



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