Flat manufacturing growth, drop in core sector industries data, lower monsoon forecast and tensions mounting over Ukraine affected the sentiment.
The HSBC survey for April showed manufacturing sector remained 'steady' even as domestic demand made up for fall in exports.
Growth in eight core sector industries decelerated to 2.6 percent in 2013-14, the lowest in almost a decade, said government data.
Investor worries over developments in Ukraine lingered on as US has already announced some sanctions and has threatened to impose more economic sanctions on key sectors of Russia's economy.
The Sensex resumed higher at 22,717.59 and moved in a range of 22,721.36 and 22,284.96 before ending the week at 22,403.89, disclosing a loss of 284.18 points, or 1.25 percent.
The NSE 50-share Nifty also dropped by 87.95 points, or 1.30 percent, to end at 6,694.80.
Shares of metal, capital goods, realty, power and auto sectors were the major losers during the week.


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