The researchers from Scripps Research Institute Scientists working with the International AIDS Vaccine Initiative said that an effective vaccine would work by eliciting a strong and long-lasting immune response against vulnerable conserved sites on the virus-sites that don't vary much from strain to strain, and that, when grabbed by an antibody, leave the virus unable to infect cells.

Dennis R Burton, professor in TSRI's Department of Immunology and Microbial Science, said that HIV has very few known sites of vulnerability, but in this work we've described a new one, and we expect it will be useful in developing a vaccine.

The study was published in the journal Immunity.

(Agencies)

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