The French government, which owns almost 20 percent of Renault, has said it wants to safeguard French interests at the automaker, which is deepening its ties with Nissan. However, Renault has warned that the government's move could damage the alliance.
Ghosn, speaking to reporters in Japan, said the capital alliance between Nissan and Renault had "zero influence" on the automakers' daily operations.
Since Renault rescued Nissan from bankruptcy in 1999, the Japanese carmaker has outgrown its parent to account for two-thirds of their combined 8 million vehicle sales and a bigger share of profit.
"We continue to work today exactly the way we were working from the beginning, with the two teams working together, developing synergies," Ghosn said. "So there's no reason for us to change."
Asked about potential partnerships with other automakers, Ghosn said the Renault-Nissan alliance had no immediate plans for any more partnerships for now.
He also said it was "too early" to consider tie-ups with non-automakers such as Google Inc which is trying to enter the auto market.
Renault-Nissan already has partnerships with Daimler AG  and Avtovaz.
Nissan's rivals Toyota Motor Corp and Mazda Motor Corp this month launched a long-term partnership amid a push by automakers worldwide to cut costs by building scale.