Paracetamol is the primary medicine used for managing pain and fever during pregnancy."This study adds to existing evidence that prolonged use of paracetamol in pregnancy may increase the risk of reproductive disorders in male babies," said lead researcher Rod Mitchell, a clinical research fellow at the University of Edinburgh.

They measured the amount of testosterone produced by the human tissue an hour after the final dose of paracetamol.They found there was no effect on testosterone production following 24 hours of paracetamol treatment.

After seven days of exposure, however, the amount of testosterone was reduced by 45 percent."Further research is required to establish the mechanism by which paracetamol might have this effect," the team concluded.The study appeared in the journal Science Translational Medicine.

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