The 30-share barometer fell by 86.44 points, or 0.39 percent, to 21,746.42 with stocks of banking, PSUs, capital goods, power, oil and gas and realty sectors leading the fall. The index had gained 58.25 points in the previous three sessions.
Similarly, the wide-based National Stock Exchange index, Nifty dipped below 6,500 level by falling 26.15 points, or 0.40 percent, to 6,497.90.
Brokers said the sentiment turned weak on funds selling amid profit-booking by retail investors in line with falling trend on the other Asian markets after the US Federal Reserve hinted that the central bank could hike interest rates earlier than expected.
In the Asian region, Japan's Nikkei was down by 0.52 percent, while Hong Kong's HangSeng shed 0.87 percent in morning trade. US Dow Jones Industrial Average ended 0.70 per cent lower in Wednesday's trade.


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