Foreign investors' concerns over retrospective taxation continued to weigh on sentiments, traders said.
FIIs had sold shares worth Rs 1,506.86 crore yesterday, as per provisional data.
Sun Pharma was the top loser on 30-share Sensex by tumbling 8.86 percent to Rs 961.60 after Japan's Daiichi Sankyo announced sale of its holding in the Indian firm.
Other pharma stocks, Cipla and Dr Reddy's fell by 0.94 percent and 2.81 percent, respectively, on the Sensex.
The index opened lower at 27,860.51 on sustained foreign funds outflows and weak quarterly earnings. However, it recovered to touch day's high of 27,976.93 in noon trade on value buying in select stocks.
A round of late selling in select bluechip stocks dragged Sensex down to touch low of 27,598.21 before closing at 27,676.04 points -- its weakest level since March 27 – down 210.17 points or 0.75 percent.
The gauge has now lost over 1,370 points in five sessions.
The NSE Nifty slipped below the 8,400-mark by falling 70.35 points or 0.83 percent at 8,377.75. It shuttled between 8,469.35 and 8,352.70, intraday.
"Domestic factors continue to drive market into further consolidation. Though FIIs selling due to tax woes influenced to an extent, Q4 results will still be the decisive factor for market in the near-term," said Vinod Nair, Head-Fundamental Research at Geojit BNP Paribas Financial Services.
Moreover, the rupee which breached the crucial 63-mark to touch a low of 63.15 at the outset, rebounded by 16 paise to trade higher at 62.75 against the dollar (intra-session).
Sectorwise, the BSE healthcare index suffered the most by falling 3.24 percent, followed by Auto at 1.31 percent, FMCG by 1.17 percent, Oil & Gas 1.08 percent, Power 0.73 percent, capital goods 0.48 percent and realty by 0.37 percent.
On the day, BSE smallcap fell by 0.32 percent, while midcap dropped by 0.45 percent.
Globally, other Asian markets ended in positive zone, while European markets were trading higher in their opening trade.

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