The best of men's and women's tennis was on display at Crandon Park with the winners of over 30 grand slam singles titles all in centre court action. (Agencies)
After Federer and Djokovic's successes, Venus Williams registered a straight sets win and Li Na advanced in a walkover, it was left to defending champion Murray to provide a bit of late night drama, taming Australian Matthew Ebden 3-6 6-0 6-1 as the clock approached midnight.
Murray, who split with coach Ivan Lendl earlier in the week, got the contest off to an unsteady start when Ebden broke him at the first opportunity and then held serve to quickly jump in front 3-0 on his way to easily taking the opening set.
After storming through the second set, Murray was broken at the start of the third which sent the Briton into a towel tossing rage as he berated himself.
The chastising had the desired result as the sixth seed immediately broke back to get on level terms and raced through the next five games to clinch a convincing victory.
"You do what you do to win a match," said Murray. "It's not always about how you play or how calm you are on the court, it's about winning the tennis match. That's what matters,” he said.
"I won the next six games after that so maybe it nothing to do with it, maybe it helped. I just got on with it and won the match," he added.
After a year's absence, fifth seeded Federer celebrated his return to the Miami hardcourts with a clinical 6-4 7-6 (4) win over towering Ivo Karlovic while world number two Djokovic launched his bid for a fourth Miami title in impressive fashion, dispatching Frenchman Jeremy Chardy 6-4 6-3.
A twice winner at Crandon Park, Federer did not visit Miami last year, taking an extended layoff before starting his season. But he looked quite at home, needing just 74 minutes to slay the 6-foot, 11-inch (2.11m) Croatian in a slugfest that featured just one break of serve.
"I was able to play a very clean match on my service games throughout, make sure I had a lot of first serves in, make sure I stayed aggressive from the baseline," said Federer.
The best of men's and women's tennis was on display at Crandon Park with the winners of over 30 grand slam singles titles all in centre court action.