The Proteas are missing both star batsman Hashim Amla and spearhead Dale Steyn for the first two matches of the five match one-day series. (Agencies)
But De Villiers insists his team are brimming with confidence, especially after they managed to square the Test series 1-1, winning the second showdown in Dubai by an innings and 92 runs.
"We didn't have much time for preparation so it’s really up for us mentally to get prepared but it's important to have a good start, get used to the conditions and adapt as quickly as possible and attack them in areas where they are not strong," said De Villiers today.
"Dale needed some rest but hopefully he will join us in good stead," said De Villiers of the paceman who returned home for rest but will be available from the third match in Abu Dhabi on November 6.
Amla returned home after the first Test match to be with his wife following the birth of their second child. The 30-year old is ranked world number one in Test rankings.
The second one-day match will be played in Dubai (November 1) while the third and fourth matches are in Abu Dhabi (November 6 and 8) and the final takes place in Sharjah (November 11).
The two teams will also play two Twenty20 internationals in Dubai on November 13 and 15.
The Proteas are missing both star batsman Hashim Amla and spearhead Dale Steyn for the first two matches of the five match one-day series.