With the real estate mogul leading with 31.8 percent support in Real Clear  Politics average of polls widely expected to win in Indian-American governor  Nikki Haley's home state, the focus is on who would get the second place.

While Texas senator Ted Cruz, who scored a surprise win in the first  Republican caucus in Iowa, has the backing of 18.4 percent Republican voters, Florida senator Marco Rubio snapping at his heels with 17.8 percent, has been endorsed by Haley.

Trump, who Thursday took on Pope Francis for suggesting he is not Christian because of his plans to build a wall on the US-Mexican border and deport  illegal immigrants and Rubio are both attacking Cruz calling him a liar and  dishonest.

"He holds up the Bible and then he lies," Trump said of Cruz Thursday. "I  think it's very inappropriate."Cruz is fighting back and dared Trump to sue him after the billionaire sent  a letter urging Cruz to stop.

The remaining three candidates are also hoping for a good performance in  South Carolina to keep their campaigns going.

Former Florida governor Jeb Bush, after losing the coveted endorsement of  Haley to Rubio, is running low on cash. His efforts this week have included campaigning with his brother, former  president George W. Bush, and his mother, former First Lady Barbara Bush.

Meanwhile, self styled Democratic Socialist Bernie Sanders is posing a tough challenge to Clinton in the Democratic caucus in Nevada.

In her first run for the White House in 2008, Clinton won the popular vote  in Nevada over then Sen. Barack Obama. The question is whether after a drubbing in New Hampshire, would she be able  to repeat the feat and put a stop to the 'Bern-mentum.'

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