Washington: A new type of nano-particle has been developed by scientists, which they say would safely and effectively deliver vaccines for diseases such as malaria and HIV-AIDS. (Agencies)
A team from the Massachusetts Institute of Technology (MIT) has developed the new particles consisting of fatty spheres that can carry synthetic versions of proteins normally produced by viruses.
According to the researchers, these synthetic particles will elicit a strong immune response, comparable to that produced by live virus vaccines, but should be much safer.
After the contact with chemicals inside human cells, the particles trigger the vesicles to unload their cargo, which slowly leaks out over the course of a month, they said.
"We can use these to deliver any synthetic vaccine very effectively to immune cells," James Moon, a researcher, was quoted as saying by LiveScience.
The team demonstrated that their strategy sparks more powerful immune responses in mice than other types of lipid spheres, achieving results comparable to the delivery of live viruses.
"All the models we tested are showing very strong and positive signs that these are working very well," said Moon.
Next, the researchers said they would test whether the technique can combat malaria and HIV-AIDS, both of which currently lack effective vaccines.
Because the major components of the drug carrier are already approved and there have been no adverse side effects reported, they are optimistic about future clinical trials in humans.
"The vaccine platform can potentially be applied to all different kinds of infectious diseases," said Moon.
The new findings were published in the journal Nature Materials.
Washington: A new type of nano-particle has been developed by scientists, which they say would safely and effectively deliver vaccines for diseases such as malaria and HIV-AIDS.