MS is a disease of the central nervous system that results in damage to the protective covering of nerve fibres. Symptoms include weakness, muscle stiffness and difficulty thinking - a phenomenon often referred to as 'brain fog'. According to the Multiple Sclerosis Foundation, MS affects an estimated 2.5 million people worldwide, researchers said.

Damage to the thalamus, a structure in the middle of the brain that acts as a kind of information hub, and its connections with other parts of the brain play an important role in the cognitive dysfunction many MS patients experience.

Researchers led by Laura De Giglio, from the Sapienza University in Rome, studied the effects of a video game-based cognitive rehabilitation programme on the thalamus in patients with MS.

Twenty-four MS patients with cognitive impairment were randomly assigned to either take part in an eight-week, home-based rehabilitation programme - consisting of 30-minute gaming sessions, five days per week - or be put on a wait list, serving as the control group.


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