Liver cells in females, and in particular those women who have attained menopause, are more susceptible to adverse effects of drugs than in males, the findings showed.It is well-known that women are more vulnerable when it comes to drug-induced liver effects, but it is the first time it has been shown that there are differences at cellular level, the study pointed out.

"Our experiments showed female cells as being more sensitive, at certain exposure times, for some of the tested drugs," the study noted.The findings are striking, clinically relevant, and emphasise the importance of considering sex-based differences in human health risk assessment.

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